Comparison of the chemical composition of the hexanics extracts from species of Croton. Biological activity
Keywords:
euphorbiaceae; crotón; extractos hexánicos; actividad antimicrobiana y GC-MS.Abstract
The species endemics Croton micradenus, Croton myricifolius and Croton spiralis among
others the genus, integrate the main populations in this Oriental region of Cuba. A wide
range of uses are attributed to the species of the genus, among which medicinal uses stand
out. Among the secondary metabolites present in Croton species, nonpolar compounds
constitute a group that has shown biological activity against pathogenic microorganisms. In
this sense, our objective is to compare the chemical composition, determine the major
components and the potential chemo-taxonomic markers; as well as, the antimicrobial
activity of the hexanic extracts of the leaves and stems of the three species, by GC-MS and
pharmacological assays. The samples tested showed activity against at least two of the four
microorganisms studied. The presence of octacosanol and palmitic acid (majority
components), as oleic acid, stigmasterol and sitosterol in the extracts of the three species
confer responsibility for the biological activity expressed.
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