Thermal Decomposition of the Peroxide acid Glutaraldehyde in Solution of Methanol, Activation Parameters and Reaction Mechanism

Authors

  • Nelly Lidia Jorge-Rodriguez Facultad de Ciencias Exactas, Naturales y Agrimensura, Universidad Nacional del Nordeste
  • Jorge Marcelo Romero-Páez Facultad de Ciencias Exactas, Naturales y Agrimensura, Universidad Nacional del Nordeste
  • Mariela Profeta–Lo Menzo Facultad de Ciencias Exactas, Naturales y Agrimensura, Universidad Nacional del Nordeste
  • Mónica Beatriz Reguera–Miranda Universidad Nacional del Chaco Austral

Abstract

Abstract This paper presents the results obtained in the study of the thermal decomposition of diperoxide acid glutaraldehyde (DPAG) in methanol solution, to determine the parameters for activation and elucidate the reaction mechanism; the importance of this type of compound is because it has now been found to have pharmacological action as bactericidal, antitumour and as antimalarials. The reaction was carried out between 130.0 to 166.0 ° C and initial concentration of 5.49 x 10-4 mol / L, it satisfies with a first order kinetic law to conversions peroxide ca. 50 %. Analysis of the reaction products and the parameter values activation contributes to postulate that the mechanism for thermolysis of DPAG in methanol solution begins with the homolytic cleavage of the peroxidic bond giving a biradical intermediate, which undergoes CO rupture giving glutaric acid and oxygen as final products.

Keywords: diperóxido, thermolysis, reaction´s mechanisms, activation.

Author Biography

Nelly Lidia Jorge-Rodriguez, Facultad de Ciencias Exactas, Naturales y Agrimensura, Universidad Nacional del Nordeste

 

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Published

2016-09-16

How to Cite

Jorge-Rodriguez, N. L., Romero-Páez, J. M., Profeta–Lo Menzo, M., & Reguera–Miranda, M. B. (2016). Thermal Decomposition of the Peroxide acid Glutaraldehyde in Solution of Methanol, Activation Parameters and Reaction Mechanism. Revista Cubana De Química, 28(3), 751–759. Retrieved from https://cubanaquimica.uo.edu.cu/index.php/cq/article/view/1544

Issue

Vol. 28 No. 3 (2016)

Section

Artículos

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