Alternative methods to quantify chloride ions as a variant to NC-ISO 2481


  • María de los Ángeles Arada Pérez Universidad de Oriente. Patricio Lumumba s/n, Santiago de Cuba, Cuba
  • Natacha Sarmiento Rodríguez Universidad de Oriente. Patricio Lumumba s/n, Santiago de Cuba, Cuba
  • Karel Yasmany Nápoles Florián UEB Laboratorio Geominera Oriente, Santiago de Cuba, Cuba
  • Leandro León Duharte Universidad de Oriente. Patricio Lumumba s/n, Santiago de Cuba, Cuba


NaCl comercial, AgNO3; determinación de haluros; métodos alternativos.


In this work, the volumetric, conductometric and potentiometric methods for the determination of Cl- ions in commercial NaCl samples were compared with the method established in NC-ISO 2481. Hg(NO3)2 was replaced by AgNO3 as the titrant in the
normalized method. The percentage of halogens expressed as Cl-, NaCl, and I- were determined. The analysis performance parameters sensitivity, and repeatability were evaluated as precision and truthfulness criteria. One way Anova as carried out, where the Cochran C test was applied to verify the homogeneity of variance, with the p-Value = 0,82, which indicated the equality of the homogeneity of the same. The p-value show in ANOVA table is 0,99, and it was confirmed that there are no significant
statistical differences between the means of the calculated percentage of NaCl.


J.C. Chou, G.-C. Ye, D.-G. Wu, C.-C. Chen, Fabrication of the array chlorine ion sensor based on microfluidic device framework, Solid State Electron. 77 (2012) 87–92.

L. Zhe, L. MING, C. Juan, Q. Xin, An all-solid-state polymeric membrane chloride ion-selective electrode with nanowires poly(3,4-ethylenedioxythiophene) as solid contact, Int. J. Electrochem. Sci. 12 (2017) 11715–11727. DOI:10.20964/2017.12.44.


Elaboración y prueba de un electrodo para la cuantificación de cloruro de potasio y bromuro de potasio. Tecnología en Marcha. Vol. 27, N° 3, Julio-Setiembre 2014. Pág 80-87. On-line version ISSN 0379-3982Print version ISSN 0379-3982

D. C. Harris. Análisis Químico Cuantitativo. 2da edición correspondiente a la 5ta ed. Original norteamericana. Editorial Reverté. S. A. Barcelona- Bogotá-Buenos Aires- Caracas-México (2001). ISBN-84-291-7222-X. p. 158-165.

R. B. R. Mesquita; FERNANDES S. M. V.; and Rangel A. O. S. S.

“Turbidimetric determination of chloride in different types of water using a single sequential injection analysis system,” Journal of Environmental Monitoring, 4 (3) (2002) 458–461. ISSN: 1464-0325.

KIM D. and CHANG, J. “Determination of stannous chloride and stannic bromide speciation in concentrated Cl− and Br− media by cyclic voltammetry,” Journal of Electroanalytical Chemistry, 785 (2017) 20–25. Online ISSN: 1873-2569 Print ISSN: 1572-6657.

TAGAMI K.; Uchida S., Hirai I.; TSUKADA H.; and Takeda H. “Determination of chlorine, bromine and iodine in plant samples by inductively coupled plasma-mass spectrometry after leaching with tetramethyl ammonium hydroxide under a mild temperature condition,” Analytica Chimica Acta, 570 (1) (2006.) 88–92.

GONZÁLEZ MENDOZA, L. Belén Altava, M. Isabel Burguete, Jorge

Escorihuela, Elsa Hernando,Santiago V. Luis, Roberto Quesada and Cristian Vicent. DOI: 10.1039/x0xx00000x. Bis(imidazolium) salts derived from amino acids as receptors and transport agents for chloride anion . This journal is © The Royal Society of Chemistry 2013. 3-8. RSC Advances.

ARADA, M.A; YAZDANI-PEDRAM M. Behavior of a polymeric liquid

membrane ion-selective electrode for chloride ion. J.Chil.Chem.Soc; 58, (3) (2013) 1842-1843. On-line ISSN 0717-9707.

TOH H. S.; Batchelor-Mcauley C.; Tschulik, K.; and Compton, R. G.

“Electrochemical detection of chloride levels in sweat using silver nanoparticles: A basis for the preliminary screening for cystic fibrosis,” Analyst, 138 (15) (2013) 4292–4297. ISSN: 0003-2654

ARADA, M. Á. Santiago Vicente Luis, Belén Altava, Francisco Galindo. Rev. Cubana Quím. Vol. 27, no. 2, mayo-agosto, 2015, págs. 119- 130. Construcción y evaluación de electrodos selectivos de iones cloruro. e-ISSN: 2224-5421.

BUJES GARRIDO J. Tesis doctoral. Desarrollo de diferentes sensores electroquímicos para la determinación de cloruro, Universidad de Burgos. Departamento de Química. Área de Química Analítica. 2017. España. DOI 10.36443/10259/5880.

XIAO J. B. “Determination of nine components in Bayer liquors by high performance ion chromatography with conductivity detector,” Journal of the Chilean Chemical Society, 51, (3) (2006) 964–967. On-line versión ISSN 0717-9707.

R. Michalsky and J. Janiszewska, "Ion chromatography - A method of choice for the determination of ionic species in water and waste waters," Problemy eksploatacji, vol. 4, pp. 93-106, 2016. ISSN 1232-9312

Pohl, C. (2017). Chapter Ten. Use of Ion Chromatography for Monitoring Ionic Contaminants inWater. En: Chemistry and Water. The Science Behind Sustaining the World's Most CrucialResource, Editor Satinder Ahuja. ELSEVIER, United States, Pag. 353–391.ISBN 97801281307666.

Patente. Martínez Julia Arcos, Silva Hugo Cunha. Procedimiento de detección y determinación de ion cloruro en muestras liquidas. Universidad de Burgos. España. ES201830271A. 2018- Publication of ES2725248B2. Status Active 2038-03-20.

Skoog D.A; Holler F.J. y Nieman T.A (1992). Principios de Análisis

Instrumental. 5ta ed. Cengage Learning. Ciudad de Madrid, España. Pág 639-671. ISBN 0-03.0020786

NC-ISO 2481. Proyecto. Guía para la validación de Métodos Químicos de Ensayo. Oficina Nacional de Normalización. Sodium Chloride for industrial use. Determinations halogens expresses as chlorine. Mercurimetric methods. La Habana, Cuba, 2001.

APHA, AWWA, WEF. Standard Methods for the Examination of Water and Wastewater. 2Nd Edition. American Public Health Association, Washington, 2012. ISBN 978-087553-013-0

Microsoft Excel, 2016 Microsoft Excel, Microsoft Office, Microsoft

Corporation, 2016. 21. Statgraphics Centurion, X.V.I. Statpoint Technologies. INC. version, 16, 17. 2009.



How to Cite

Arada Pérez, M. de los Ángeles, Sarmiento Rodríguez, N., Nápoles Florián, K. Y., & León Duharte, L. (2023). Alternative methods to quantify chloride ions as a variant to NC-ISO 2481. Revista Cubana De Química, 35(3), 443–460. Retrieved from




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