Isolation and characterization of metabolites from Croton linearis Jacq. leaves

Authors

  • Lic. Jesús García-Díaz Facultad de Ciencias Naturales, Universidad de Oriente, Santiago de Cuba
  • Dr. C. Julio C. Escalona-Arranz Facultad de Ciencias Naturales, Universidad de Oriente, Santiago de Cuba
  • Dr. C. Mario G. do Carvallo Instituto de Ciencias Exactas, Universidad Federal Rural de Río, Río de Janeiro
  • MSc. Julio Rojas-Vargas Facultad de Ciencias Naturales, Universidad de Oriente, Santiago de Cuba
  • MSc. Roberto Machado-García Facultad de Ciencias Naturales, Universidad de Oriente, Santiago de Cuba
  • Lic. Jorge de la Vega-Acosta Centro de Toxicología y Biomedicina, Universidad de Ciencias Médicas, Santiago de Cuba

Abstract

From an ethanolic extract of Croton linearis Jacq. leaves were isolated and identified a total of 7 compounds:  two long chain alcohols:  2-methyl-tretradecan-2-ol  (1) y el hexacosanol (3); a linear saturated hydrocarbon: tetracosane (2); three fatty acids: stearic (4), 5,8 -dien-tetradecanoic (6) and oleic acid (7); as well as a tri -methoxylated flavone: 5-hydroxy-3,7,4′-trimethoxyflavone (5).  Structures of the compounds were elucidated by  spectroscopic techniques as  Nuclear Magnetic Resonance 1D and 2D (1H and 13C),  as well as Gas Chromatography/Mass Spectrometry and Kovats retention indexes when necessary. The substituent positions were assigned based on combination of heteronuclear HMBC and HMQC as well as homonuclear1H-1H-COSY experiments. All identified compounds constitute a first report for the specie in study.

Keywords: Croton linearis, metabolites, isolation, flavone.

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Published

2015-10-30

How to Cite

García-Díaz, L. J., Escalona-Arranz, D. C. J. C., do Carvallo, D. C. M. G., Rojas-Vargas, M. J., Machado-García, M. R., & de la Vega-Acosta, L. J. (2015). Isolation and characterization of metabolites from Croton linearis Jacq. leaves. Revista Cubana De Química, 27(3), 289–301. Retrieved from https://cubanaquimica.uo.edu.cu/index.php/cq/article/view/245

Issue

Vol. 27 No. 3 (2015)

Section

Artículos

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