EXPERIMENTAL PROCEDURE FOR DETERMINING DYNAMIC VISCOSITY USING PROTONIC RELAXATION RATE
Keywords:
dynamic viscosity; proton relaxation rate and hematologyAbstract
This work aims to evaluate the application possibilities of Nuclear Magnetic Resonance in
Hematology, using the spin-spin proton relaxation rate (R2) at 4 MHz and 20 ºC to evaluate the
dynamic viscosity and identify the mathematical dependence between them, which will allow to
propose an experimental procedure for these purposes. Different solutions of glycerin and blood
plasma were evaluated to establish the mathematical relationship between viscosity and relaxation
rate, finding a linear dependence between both. It was shown that it is essential to build the
calibrations used in plasma samples, to appropriately take into account the fraction of water bound
to proteins, a parameter that determines the relationship between the magnitudes studied. In
addition, an experimental procedure is achieved that sets the guidelines for the application of the
method in patients affected by multiple myeloma and sickle cell anemia.
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Copyright (c) 2025 Yulianela Mengana-Torres, Manuel A. Lores-Guevara, Yamilka Alonso-Geli, Lidia C. Suárez-Beyries, Norberto Rodríguez-Suárez
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