Chemical composition and larvicidal activity of cashew nutshell ethanolic extract against mosquito larvae

Authors

  • Jesús Rafael Rodriguez Amado Laboratório de Pesquisa em Fármacos. Faculdade de Ciências da Saúde. Universidade Federal do Amapá, Macapá, AP. Brasil
  • Raimundo Nonato Picanço Souto Laboratório de Arthropoda. Faculdade de Biologia. Universidade Federal do Amapá, Macapá, AP. Brazil
  • Miriam Santos Magalhães Laboratório de Arthropoda. Faculdade de Biologia. Universidade Federal do Amapá, Macapá, AP. Brazil
  • Julio César Escalona Arranz Departament of Pharmacy, University of Oriente, Santiago de Cuba, Cuba
  • Jose Carlos Tavares Carvalho Laboratório de Pesquisa em Fármacos. Faculdade de Ciências da Saúde. Universidade Federal do Amapá, Macapá, AP. Brasil

Abstract

The goal of this work is to evaluate the chemical composition and the larvicidal activity of an extract from the nutshell (Anacardium occidentale L.) against Aedes aegypti and Culex quinquefasciatus larvae. A Hydro-ethanolic extract was prepared by maceration using 1 g of cashew nutshell in 3 mL of ethanol 70 %. The larvicidal effect and the acetylcholinesterase inhibitory activity of the extract were evaluated. The extract content includes phenolic compounds, coumarins, quinones, anthocyanidins, triterpenes, steroids, flavonoids, saponins, lipid compounds, aliphatic acids, and terpenoids. The larvicidal activity of the extract (LC50) for A.aegypti was 35,81 ppm and 40,21 ppm for A. aegypti (Macapá and Rockefeller strains), and 21,47 ppm for C.quinquefasciatus. The IC50 for the AChE inhibitory test was 43,27±2,22 ppm. The evaluated extract presents a good AChE inhibitory activity and a potent larvicidal activity. The larvicidal effect could be associated with the AChE inhibitory activity of the extract.

Keywords: larvicidal activity, nutshell ethanolic extract, mosquitoes.

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Published

2017-10-06

How to Cite

Rodriguez Amado, J. R., Picanço Souto, R. N., Santos Magalhães, M., Escalona Arranz, J. C., & Tavares Carvalho, J. C. (2017). Chemical composition and larvicidal activity of cashew nutshell ethanolic extract against mosquito larvae. Revista Cubana De Química, 29(3), 330–340. Retrieved from https://cubanaquimica.uo.edu.cu/index.php/cq/article/view/2938

Issue

Vol. 29 No. 3 (2017)

Section

Artículos

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